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What it does: Establishes higher felony classifications and mandatory penalties for the manufacturing, dispensing, sale, and possession of fentanyl and certain synthetic opioids. Makes possession of any amount of fentanyl a felony offense and limits sentencing exceptions for distribution cases that result in death.

Background: Colorado's 2019 drug policy reform downgraded many drug possession charges. This measure rolls back those changes specifically for fentanyl in response to the ongoing overdose crisis. It also requires court-ordered treatment for certain low-level possession offenses.

To pass: Simple majority (50% + 1). Backed by Advance Colorado with 180,000+ signatures submitted.

What it does: Requires state and local law enforcement to notify the U.S. Department of Homeland Security within 72 hours of charging an individual when: (1) the person is unlawfully present in the U.S. or their immigration status cannot be determined, and (2) they are charged with a violent crime or have a prior felony conviction on record.

Background: This constitutional amendment would override existing Colorado laws that restrict local law enforcement cooperation with federal immigration authorities. It effectively ends "sanctuary" policies for violent offenders and repeat felons.

To pass: Requires 55% approval (constitutional amendment threshold). Backed by Advance Colorado with 142,000+ valid signatures.